Based on the previous lessons which involved the hormonal control of follicle maturation, ovulation, endometrial development, FSH, LSH control of hormone release, and the story of what happens when exogenous estrogen and progesterone is used. The history of the development of the modern oral contraceptive from it's derivation from Mexican Cactus plants to the micromilligram drugs now in use was discussed. The effects on the development of the follicle, the release of the ovum and the endometrial thickening was shown on a graph showing each of those changes from the normal.