The Navajo Nation has surpassed New York and New Jersey for the highest per-capita coronavirus infection rate in the US - another sign of Covid-19's disproportionate impact on minority and improverished communities. This is a tragic repeat of how smallpox decimated indigenous peoples in the Americas throughout the 16th century, during the Columbian Exchange/European Age of Exploration. The Navajo Nation, which spans parts of Arizona, New Mexico and Utah reported a population of 173,667 on the 2010 census. With sick citizens, the Native American territory has 2,304.41 cases of Covid-19 per 100,000 people. We looked at why there is a high rate of infection and the measures being taken to help the Navajo people. There are many Native American communities that are suffering greatly during the pandemic.