Hand out and explain written assignment due for Thursday.
Discuss requirements for a drug to reach its target organs.
Using a chart of organs and blood volume, indicate that organs
differ widely in terms of proportion of systemic blood they receive, and therefore the amount of drug they will require to reach a therapeutic level.
Discuss plasma protein binding of drugs.
Indicate that drug concentration is best measured as a level of drug in the blood plasma, and can best be monitored this way.
Examine a case study involving effective dose and lethal dose levels of an imaginary drug, and why a second drug may increase the possibility of a lethal effect occurring.