Discuss the paper which was read by Nina last night. This included what is gaba, how does gaba work, what is the relationship of gaba to glutamate, what medical conditions are associated with changes in the level of gaba, and what medications target gaba.
View a diagram of the gaba receptor with its allosteric sites and discuss how and why benzodiazepines and barbiturates act.
Discuss inhibitors of gaba metabolism which results in agonism with the major effects of gaba secretion. These are calming, anxiolytic, lowering stress and fear, muscle relaxation.
discuss the effects of gaba agonists. List how different Benzo's produce different effects, sometimes based on dose. These include sedation, hypnotic effect, anxiolytic effect, and muscle relaxation.

View a diagram of a typical GABA receptor, showing the various binding areas.
Read an abstract about how GABA functions on the CNS, its affect on anxiety, depression, muscle tone, and mood.
Discuss how the benzodiazepines and barbiturates bind with the receptors and act as partial agonists.

Review of the human nervous system in its anatomical and functional division.
Division into the central nervous system and the peripheral nervous system.
Division into the somatic and visceral sensory divisions along with the motor division.
Review from a diagram the structure of the neuron.
List the common neurotransmitters and the areas they are released at.
Discuss GABA and Glutamate as inhibitory and excitatory neurotransmitters.

Review by outline the mode of action of the original HIV antiviral medication.
Outline and discuss the 6 targets which the different antivirals attempt to be active at.
Read the report on the use of and reason for multiple antiviral drug treatment.

Based on the information from the previous class, and integrated together with today's lesson, the MOd of both the life cycle and the integration of viral DNA into host genes can be evaluated.

Use the human immunosuppressant virus as the example to show the mode of actions of antivirals which attack the transcription of viral RNA into DNA.
Briefly discuss the structure of RNA/DNA nucleotides.
Briefly discuss the reading of the code in RNA which allowss for the production of specific protein enzymes.
Outline reverse transcriptase, integrase, and protease, and their function in viral replication.
Discuss the classic reverse transcriptase inhibitor, Ziduvidine.

Discussion of human immunosuppressant virus and its conversion into the disease of AIDS. The structure of the viral particle is examined in diagrams and the stages of infections are listed and explained.
The life cycle of a typical virus is outlined from attachment to egress from the cell.

Discuss how virus infections are the number one infections worldwide in terms of morbidity and mortality.
List reasons for this high rate, especially in underdeveloped countries. These will include poor public sanitation as well as lack of vaccines and expensive drugs for treatment.
Using diagrams, discuss the anatomy of the virion and how pharmacological treatment is designed to interrupt some physiological processes, like reproduction, in order to kill or control the replication of the viral particle.

Examine the physiology of viral replication and the steps targeted by current antiviral drugs.
Discuss the viral life cycle, the anatomy of a typical viral particle, DNA and capsid, the structural unit of a virus and the membrane proteins which allow for binding to a host cell.
Introduce the retrovirus and the steps which bring it from attachment to viral infection.

List and discuss the three common groups of worm parasites which can infect humans. Discuss their mode of entry and diseases caused by each.
Discuss the pharmacology of some standard drugs, like ivermectin, used in the treatment. Show how the drugs interfere with the nerve transmission within the parasite and destroy any larvae