Read and discuss printouts dealing with herbs and botanicals which affect liver enzyme metabolic pathways.
Begin looking at the MKULTA project from the 1960's which involved mind control using specific drugs.
view video
Assignment
study for quiz fri. read printout for discussion
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
interesting discussion and video. Cole has good instincts and is working well
Discuss drug effects as being individual, and the reasons for the individuality.
Discuss effects as being Beneficial or Harmful. Stress that harmful is not the same as a side effect.
Outline what makes a drug beneficial by definition and talk about allergic response and anaphylactic shock as harmful effects
Assignment
n/a
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
Cole was very much into the lesson today, taking good notes and asking pertinent questions. More like his old self.
Chart and graph a percent concentration v time for a "standard oral drug"
Illicit what is occuring at different time intervals to the concentration in the blood
Discuss the idea of half life of a drug and how it relates to drug action time.
Assignment
Research report on vitamins and vit. deficiencies
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
Cole was like his old self today. He was relaxed and asked good questions, some of which we will research later on.
Discuss how min. therapeutic level is individual
graph a time v response curve and discuss each time interval
relate how the min. therapuetic level is individualized by blood testing
Discuss the advantages to long acting drugs
Assignment
n/a
Session Minutes
45
Minutes Student Attended
45
Lesson Comments
Cole was attentive but a little pre-occupied. He did answer questions.
Quiz on previous material-
discuss bioavailability- factors which will alter bioavailabilty and how to overcome them.
discuss therapeutic dose range as a dosage factor
Assignment
take home exam
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
I decided to have Cole take the exam home to answer those questions he had a problem with.
Discussion was kind of one-sided today- However, he did seem to become more involved as the class went on.
discuss and list the objectives of drug therapy
list terms for definition
discuss maximum therapeutic level and dose
discuss toxicity and drug underdosing
relate warfarin discovery as rat poison and eventually as a blood clotting supprssor.
Discuss need to monitor blood and urine for dosage
Assignment
na/
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
Cole was MUCH better today. He was ready to learn and take notes and ask questions.
Discus terms
dosing, maximum therapuetic dose, what drug treatment must accomplish and how.
Assignment
/na
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
Cole is extremely depressed. I spoke with him for the better part of the hour. He seems to need professional counseling,though he says it will not help. I did what I could and I hope something helped.
List and discuss the process involved in metabolism. Discuss the factors whcih affect metabolism and which affect liver enzyme production. Illicit what will happen if the enzymes are increased or decreased, and how this may occur.
Assignment
n/a
Session Minutes
45
Minutes Student Attended
45
Lesson Comments
All notes were taken and the objectives completed.
Def. of distribution
Factors which will affect distribution- disease, age, general health-arteriosclerosis-coronary artery disease-hypotension and hypertension
Plasma binding and free drug
blood brain barrier
Assignment
research blood brain barrier-pathophysiology and affects of chemicals
Concentrate on the factor of solubility as it affects absorption.
List and discuss the factors which affect solubility- drug form, pH, ionic, lipid, hydrophilic, size of particles.
Assignment
read ahead in chapter 2 metabolism
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
Interesting discussion- Cole is taking good notes and responds nicely to questions
