Discuss the history of aspirin by relating the chewing of willow bark to ease pain and inflammation.
Show how the active ingredient in the bark was Salicin, or salicylic acid.
Examine why salicylic acid was good for headache but caused gastric distress and ulcers.
Discuss the chemistry of acetylating the salicylic acid to form a compound which was much easier on the stomach, acetylsalicylic acid, or aspirin.
View the synthesis.
Discuss Bayer and his dye business prior to WWI.