Discuss the major receptor types for opioid action- concentrate on the Mu1 receptor and the secretion of GABA. Derive the formula for the amino acid and discuss how stimulation of the receptors brings about decreases in secretion of gaba and increases in dopamine secretion with the accompanying affects
Assignment
look up opium poppy
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
Trevor is not feeling very well today- has a terrible cold but was able to complete the class and take notes-We discussed some future plans
discuss and arrive at a definition for pain. Discuss aspects of the definition, concentrating on physical tissue damage and emotional pain
Illicit ways of describing pain- intensity, location and length
discuss chronic pain syndrome
Assignment
research MKULTRA
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
Trevor is very knowledgable about many aspects of what we discussed in class He continues to ask poignant and interesting questions.
discuss the electrochemical nature of a nerve impulse and how it is the same impulse regardless of the response. Illicit that the response will be dependent on the type of receptor site activated by the nerve impulse.
discuss the effects of the sympathetic n.s. and the neurotransmitters involved, as well as the effects of the sympathetic system and the neurotransmitters involved.
Assignment
complete take home
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
Objectives completed. Trevor initiated a side discussion regarding nerve transmission and the effect of depolarization on the nerve cell. He is very interested in the chemistry of the systems and the chemistry of the drugs and how the chemistry affects the response.
discuss the anatomy of the nervous system, the major divisions and the anatomy and physiology of the neuron. This is needed in order to proceed with a study of analgesics and antidepressasnts
Assignment
15 questton take home
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
Trevor has good recall from biology- asks interesting questions- the review of the nervous system will be kept brief
using printouts, discuss the structural formula of the quinolone antibiotics, their overuse and adverse affects and their mode of action in preventing dan replication within the cell.
look at ciprofloxacin as the typical molecule of this class.
Assignment
read the handout on cipro and be able to discuss adverse
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
Interesting discussion on the chemical makeup and the use of antibiotics in general
referring to printouts- discuss macrolids, the structure of the lactam ring, the effect of changing the structural formula on half life and dosage. Some specific uses of specific macro lids
Assignment
read paper on zithromycin
Session Minutes
60
Minutes Student Attended
60
Lesson Comments
discussed some answers to questions posed on mon. by trevor. Related previous chemistry work to the structure of the lactam ring and particularly the macro lid structure.
