Present the partial oxidation formula depicting the oxidation of ethanol into ethanal, also called acetaldehyde. Outline how the enzyme alcohol dehydrogenase metabolizes the alcohol into acetaldehyde, and then the enzyme acetaldehyde dehydrogenase oxidizes that into acetyl coenzyme A. Present the physiological effects acetaldehyde has on the body. Present how the drug disulfuram inhibits the conversion of acetaldehyde to coenzyme A which causes severe nausea and vomiting, This acts as the stimulus for alcoholics not to drink when they are on the drug.
Introduce carboxylic acids, the functional group and nomenclature. Outline the formation of organic salts from these acids, along with their ionization.
Discuss phenol compounds, the general formula and specifically the use of phenol by Dr.Lister as an antiseptic in the mid 1800's. Introduce the amino group, how it its derived from ammonia, and the general formula for amines. Discuss some simple amine compounds and how they are named. Show the formula for aniline dye and amines produced when decomposition occurs in animals. Introduce the functional group for aldehydes, view the formula for formalin and discuss formaldehyde as a preservative
Outline the structural formula for a phenol. Discuss some uses for this class of compounds, as well as preparation. Introduce the functional group called ethers. Use the first two ethers in a series to demonstrate the formula and the nomenclature. Discuss how ether is a general anesthetic and the stages of anesthesia. Introduce the nomenclature for ethers
Continue with the study of organic alcohols by introducing polyhydroxyl alcohols, alcohols with 2 or 3 hydroxyl groups substituted onto alkane molecules. Discuss the nomenclature of these alcohols. Introduce glycerol, trinitroglerol, and glycols.
Discuss their use as antifreeze, explosives, and humectants.
Outline both alkyl and aryl halide substitutions. Examine the formation and structure of the general anesthetic Halothane. Sketch how the hydroxyl functional group can replace a halide from an alkane halide to form an alcohol. Discuss the formation and properties of both methanol and ethanol alcohols. Show how isopropyl alcohol is formed from propene and water under pressure and temperature. Discuss and view the structural formulas of primary, secondary, and tertiary alcohols.
Outline the functional group which determines an organic alcohol. Discuss how the alcohols are formed from halogen substituted alkanes reacting with hydroxyl containing bases. Examine and explain the two simplest alcohols, methanol and ethanol. Sketch their formulas and discuss how they are synthesized using heat, pressure and water. Introduce primary, secondary, and tertiary alcohol structures
Session Minutes
45
Minutes Student Attended
45
Lesson Comments
Unable to connect on line with Joshua. Some error in the Office 365 connection. NIcole has contacted microsoft to try and correct
Discuss how alcohols are produced by hydroxyl substitution onto an organic halide. Examine the structures of ethanol and methanol and how they are synthesized, along with their properties of polarity and water solubility, and toxicity. Show the synthesis of isopropyl alcohol from the olefine ethene. Elicit the general formula for an orgainc acid, a secondary acid and a tertiary acid.
Discuss and show examples of halogenation substitutions on organic hydrocarbons which lead to the synthesis of hydrocarbon halide compounds. Use a general formula and specific formulas to indicate the substitution replacements. Discuss substitutions onto a Benzene molecule to produce some common volatile substances such as toluene and xylene. Draw the structure for the trinitro compound of methyl benzene which becomes the common named compound trinitro toluene or TNT.
Session Minutes
45
Minutes Student Attended
45
Lesson Comments
Began the class by answering textbook chapter questions.
Review hw answers. Discuss structural and molecular formulas for a series of Benzene compounds. Introduce official IUPAC names as well as common chemical names and traditional names. Explain Alkynes bonding. Introduce functional organic group definition and explain the first group as the halogens. Examine the nomenclature by using examples, discuss physical property differences, isomers, and alcohols. From a number of structural formulas, derive the correct name, and vice versa
Introduce the chemistry of alkyne hydrocarbons, and the placement of triple bonds. Discuss the chemistry of Benzene, its molecular and structural formula. Diagram how it exists as a resonance structure, with the double bond rotating between the six carbons in the planar hexoganal structure. Build a molecular model to show the planar structure.
Assignment
Chapt 21 unit 5 questions
Session Minutes
45
Minutes Student Attended
45
Lesson Comments
Discussed test results from last week and ways to improve