Discuss the history of aspirin by relating the chewing of willow bark to ease pain and inflammation.
Show how the active ingredient in the bark was Salicin, or salicylic acid.
Examine why salicylic acid was good for headache but caused gastric distress and ulcers.
Discuss the chemistry of acetylating the salicylic acid to form a compound which was much easier on the stomach, acetylsalicylic acid, or aspirin.
View the synthesis.
Discuss Bayer and his dye business prior to WWI.
View the structural formula for aspirin.
Show how it is formed by the acetylation of salicylic acid to form acetylsalicylic acid. (ASA)
Discuss the history of the discovery and synthesis of Aspirin.
View the aspiring structure and compare it to other anti-inflammatory chemicals.
In today's class, we finished our assignment that covers the topic of writing chemical symbols and formulas. This included a drawing portion that corresponded to his answers on the worksheet. Andrew did a great job answering all of the questions I had for him.
Review formation and nomenclature of esters.
Introduce Benzene as a cyclic aromatic hydrocarbon, which forms the backbone of many organic products.
Discuss penicillin and its discovery;
Show how phenol is an alcohol.
View the structure of salicylic acid.
Show how it can become an ester, and form Aspirin
Sketch the cyclic structure of benzene, C6H6.
Discuss phenol and show its structure.
Discuss salicylic acid and display its structure.
Review how esters are formed.
Show how an acetyl group is attached to the salicylic acid.
Indicate this is acetyl salicylic acid- Aspirin.
In today's class, Andrew learned how to write chemical symbols and formulas using the elements on the periodic table. He then completed an activity that worksheet that reviews this information and had a fun interactive coloring section.
Review structures and nomenclature of organic alcohols and organic acid functional groups.
Discuss the formation, structure, and properties of compounds called esters.
Indicate that esters, as a class, possess fragrant aromas.
Outline the use of these artificial fragrances in cosmetics, food, and shampoos.
View the lab synthesis of a typical ester.
Session Minutes
45
Minutes Student Attended
45
Lesson Comments
On line with Bobby. Graded exam from yesterday showed only 5 out of 20 questions answered correctly
Review functional units and nomenclature of organic alcohols and acids.
Outline how an ester is formed from the reactions between an alcohol and an acid.
Discuss the fragrances of esters, and how they are used in perfumes, cosmetics, and as food fragrances for enhancement.
View the lab procedure used to synthesize an ester.
